About Nail Psoriasis

Overview
Nail psoriasis is a condition that occurs in people with psoriasis, which is an immune-mediated condition where the immune system mistakenly attacks healthy tissue, causing inflammation and faster skin cell growth. This can lead to the formation of plaques and scales on the skin. Psoriasis can affect various parts of the body, including the nails and joints. It is estimated that about 50% of people with psoriasis have nail involvement, and close to 90% will experience nail psoriasis at some point in their lives. Nail psoriasis can cause symptoms such as crumbling, pitting, discoloration, and separation of the nail from the nail bed. It can affect both fingernails and toenails. Treatment options for nail psoriasis include corticosteroids, topical ointments, and oral medications. If you notice any signs of nail psoriasis, it is important to contact a doctor or dermatologist for evaluation and appropriate management. Treatment can help alleviate symptoms and prevent worsening of the condition.
Causes and Risk Factors

Nail psoriasis is a condition that affects the nails and is often associated with psoriatic arthritis. The causes of nail psoriasis are not fully understood, but researchers have identified several risk factors that may contribute to its development.

Non-modifiable risk factors are factors that cannot be changed or controlled. Non-modifiable risk factors for nail psoriasis include:

  • Psoriasis: People with psoriasis, a chronic skin condition characterized by red, itchy patches of skin, are more likely to develop nail psoriasis. The severity of psoriasis symptoms, such as severe psoriasis or psoriasis that affects the scalp or buttocks, can increase the risk of developing nail psoriasis.
  • Genetic factors: There is evidence to suggest that certain genetic factors may play a role in the development of nail psoriasis. If you have a family history of psoriasis or nail psoriasis, you may be at a higher risk.

Modifiable risk factors are factors that can be influenced or changed. Modifiable risk factors for nail psoriasis include:

  • Obesity: Being overweight or obese can increase the risk of developing nail psoriasis. Studies have shown that there is a correlation between obesity and the development of psoriatic arthritis, which often accompanies nail psoriasis.
  • Smoking: Although studies have shown conflicting results, smoking has been identified as a potential risk factor for developing nail psoriasis. Quitting smoking may help reduce the risk.
  • Alcohol use: Excessive alcohol consumption has also been suggested as a possible risk factor for nail psoriasis. However, research on this subject has produced mixed results.
  • Infections and injuries: Certain infections, such as infectious diarrhea or infections leading to hospitalization, as well as injuries or trauma that require hospitalization or result from heavy lifting, may increase the risk of developing nail psoriasis.
  • Stress: Psychological stress has been identified as a potential risk factor for nail psoriasis. Managing stress through relaxation techniques and seeking support can help reduce the impact on your overall health.
Symptoms

Symptoms of nail psoriasis may include:

  • Yellow discoloration: The nails may develop a yellowish tint, particularly at the tips.
  • Ridging, pitting, or crumbling: The nails may become rough, have small pits, or start to crumble.
  • Skin symptoms: Along with nail changes, individuals with nail psoriasis may also experience skin symptoms such as patches of thickened, scaly skin that are itchy and painful.

As nail psoriasis progresses or becomes more severe, the following symptoms may occur:

  • Nail separation: The nails may start to separate from the nail bed, causing discomfort and changes in appearance.
  • Blood under the nails: Sometimes, blood can accumulate under the nails, leading to a dark discoloration.
  • Joint swelling and pain: In some cases, nail psoriasis can be associated with psoriatic arthritis, which causes joint swelling, stiffness, and pain.

It's important to note that not everyone with nail psoriasis will experience all of these symptoms. The severity and progression of nail psoriasis can vary from person to person. If you notice any of these symptoms or changes in your nails, it's a good idea to consult a healthcare professional for an accurate diagnosis and appropriate treatment.

Diagnosis

To diagnose nail psoriasis, doctors commonly perform the following examinations, tests, and procedures:

  • History and Physical Examination: Your doctor will take a detailed history about any symptoms or factors that could be contributing to your condition. They will carefully examine your nails and surrounding skin for any typical changes associated with nail psoriasis. They will look for symptoms such as pitting, discoloration, thickening, crumbling, or separation of the nail from the nail bed.
  • Clinical Indices: Doctors may use clinical indices like the nail psoriasis severity index (NAPSI) or the modified NAPSI (mNAPSI) to assess the severity of Nail Psoriasis. These indices provide a standardized way to evaluate the extent of nail involvement.
  • Biopsy and culture: In some cases where symptoms are not typical or to rule out other possible skin disorders, your doctor may recommend a biopsy and a culture. During a biopsy, a small sample of skin or nail is taken and examined under a microscope in a laboratory. This can help confirm the diagnosis of nail psoriasis and exclude other conditions such as fungal infections.

It's important to note that these diagnostic examinations should be performed by healthcare professionals experienced in dermatology or rheumatology. They play a crucial role in accurately diagnosing nail psoriasis and determining its stage or severity. If you suspect you have nail psoriasis, it's best to consult with a healthcare provider who can guide you through the diagnostic process based on your specific symptoms and medical history.

Treatment Options

The goals of treatment for nail psoriasis are to relieve symptoms, improve the skin, prevent the condition from worsening, treat any nail changes, and manage and reduce joint pain if a person has psoriatic arthritis. There are several treatment options available that can help achieve these goals.

  • Topical creams: Medicated creams can be applied directly to the affected nails and nail bed. These creams may contain medications such and corticosteroids, retinoids or calcineurin inhibitors to slow the growth of cells or reduce inflammation and damage. Some creams may also contain vitamin D. The creams work by alleviating symptoms in the nail and nail bed, improving the skin, and preventing new lesions from occurring.
  • Steroid injections: Corticosteroid injections can be recommended by doctors to help relieve inflammation in the nails. However, due to their potential severe adverse effects, doctors prefer to limit their use. These injections may be painful and can weaken the surrounding nail or matrix after discontinuation. They target specific joints and can be a fail-safe option when other treatments don't work.
  • Biologics: Biologic TNF-alpha inhibitors have been shown to be effective in the treatment of nail psoriasis.
  • Phototherapy: This procedure involves shining UV rays on the nails to slow down the growth of skin cells and alleviate some symptoms. It can be performed in a clinic or recommended for home use with specialty equipment. Phototherapy helps stop symptoms from affecting the nails and improves overall skin condition.

In addition to these treatments, lifestyle behavior changes can also contribute to managing nail psoriasis. These changes may include:

  • Keeping nails clean and trimmed
  • Avoiding trauma or injury to the nails
  • Protecting nails from excessive moisture or dryness
  • Wearing gloves while doing household chores or working with chemicals
  • Quitting smoking, as it can worsen psoriasis symptoms

It's important to note that there is no one-size-fits-all treatment for nail psoriasis. A person should work with a dermatologist to determine which treatment options are best for them based on their specific condition and needs.

Progression or Complications

Nail psoriasis is a long-term condition that can improve for a while and then worsen again, similar to other forms of psoriatic disease. The natural progression of nail psoriasis over time can vary from person to person. Some individuals may experience periods of remission where their symptoms improve or even disappear, while others may have persistent or worsening symptoms.

Complications of nail psoriasis include psychological distress, difficulty using the hands for certain tasks, and a higher risk of infection due to nail damage. The psychological distress may arise from the visible changes in the nails, which can affect a person's self-esteem and confidence. Difficulty using the hands for tasks like gripping objects or performing fine motor movements can impact daily activities.

It's important to consult with a healthcare professional or dermatologist before starting any treatment for nail psoriasis. They will be able to assess your individual situation and recommend the most appropriate treatment options based on your specific needs and preferences.

While treatment can help manage nail psoriasis, it's important to note that some treatments may have adverse effects. Working closely with your healthcare team will allow you to find the right treatments with minimal side effects.

Remember that everyone's experience with nail psoriasis is unique, so it's essential to work with a healthcare professional who can provide personalized guidance and support throughout your journey with this condition.