How COVID-19 Impacts Immunocompromised People

Overview

COVID-19 is a respiratory illness that can have a significant impact on people who are immunocompromised (have weakened or impaired immune systems). Most people who get COVID-19 will have mild illness; however, some people develop severe disease affecting the lungs and other parts of the body and require hospitalization.

People who are immunocompromised include those who:

• Are receiving active treatment for cancer
• Have blood cancers, such as lymphoma and leukemia
• Have or are currently receiving immunosuppressive therapy for organ transplant, including high dose corticosteroids and many cancer chemotherapeutic agents.
• Have a moderate or severe primary immunodeficiency condition
• Have AIDS or untreated HIV infection

People who are immunocompromised and also have other risk factors for severe COVID-19 are at even higher risk for severe complications.

Preventive measures to help reduce this population’s risk of getting COVID-19 include:

• Avoiding close contact with people who have COVID-19 or may have been exposed to COVID-19.
• Staying up to date with COVD vaccinations. This includes receiving updated vaccine for new virus variants. Check with a healthcare provider for guidance regarding updated vaccines, when to get vaccinated, and recommended number of vaccine doses based upon individual factors.
• Practice good hand hygiene by washing hands with soap and water or use hand sanitizer if soap and water aren’t available.
• Avoiding large gatherings and maintaining physical distance from others when possible.
• Wearing a well-fitting mask that covers the nose and mouth
• Cleaning and disinfecting frequently touched surfaces daily

People who are immunocompromised who are experiencing symptoms should take prompt action by:

• Contacting their healthcare provider: The healthcare provider can advise on testing, interpreting results, and, if needed, initiation of supportive care and treatment to help reduce the chances of developing severe COVID-19.
• Following medical advice
• Isolating and protecting others

It is always important for individuals to consult with their healthcare provider for personalized advice and recommendations based on their specific medical condition.