Medication Options to Treat Diverticulitis

Diverticulitis Medication Options

Diverticulitis [dye-vur-tick-yuh-LIE-tiss ] is a condition in which small pouches in the wall of the digestive tract, called diverticula, become inflamed or infected. These pouches are most often found in the colon.

There is no single “best” medication for diverticulitis. Treatment depends on how severe the symptoms are, whether there are complications, and a person’s overall health. Some mild cases may improve with rest, fluids, and a temporary change in diet, while others may need antibiotics or treatment in the hospital.

The main treatment of diverticulitis flares is bowel rest and dietary management. There are also a few diverticulitis medications used to treat the condition each with its own effect and potential side effects. Here is a breakdown: each with its own effect and potential side effects.

  • Antibiotics may be used to treat diverticulitis when symptoms are more severe, do not improve, or when a person has a higher risk of complications. They help treat a suspected bacterial infection. Not every mild case of diverticulitis needs antibiotics. The length of treatment can vary depending on the antibiotic prescribed and the person’s situation. Possible side effects include diarrhea, nausea, rash, or allergic reactions.
  • Acetaminophen: This over-the-counter pain reliever may help ease pain during a diverticulitis flare. It is generally safe when taken as directed, but taking too much can cause serious liver damage. Avoid using nonsteroidal anti-inflammatory drugs (NSAIDs) as they may worsen diverticulitis symptoms.
  • Tricyclic antidepressants: In some people, low doses of these medicines may be used after an acute episode of diverticulitis to help with ongoing belly pain or bowel symptoms. They do not treat the infection or inflammation itself. Possible side effects may include sleepiness, dry mouth, constipation, or dizziness.
  • Antispasmodic medications: These medicines may help reduce cramping or spasms in the bowel for some people. They do not treat infection or inflammation, so a healthcare professional can help decide whether they are appropriate.

Before taking any medication for diverticulitis, talk with a healthcare professional. The right medication and dose can depend on your symptoms, overall health, other medicines you take, and whether you have any complications. A healthcare professional can help choose the safest option for you and check for possible side effects or drug interactions.

Seek urgent medical care if you have severe or worsening belly pain, fever, repeated vomiting, a swollen or hard belly, blood in your stool, dizziness, fainting, or symptoms that are not getting better.