Treatment Options for Systolic Heart Failure

Systolic heart failure is a type of left-sided heart failure, also known as left-ventricle heart failure. It occurs when the left side of the heart does not pump blood as well as it should, so less blood moves around the body. Doctors measure this by looking at the ejection fraction, which shows how much blood the left side of the heart pumps with each beat. A lower ejection fraction means the heart isn’t pumping as strongly.

The objective of treatment for systolic heart failure is to improve the quality of life, reduce the risk of hospitalizations, relieve symptoms, and help the heart work better.

While there is currently no cure for systolic heart failure, medications can help slow down the progression of the condition and control its symptoms.

• By taking prescribed medications, patients can improve their heart's ability to pump, widen blood vessels, and reduce sodium and water retention in the body.
• These medications work by blocking beta receptors and interrupting angiotensin converting enzyme, which relaxes blood vessels and reduces extra sodium and water buildup in the body.
• It is important to always follow your doctor's instructions and take your medication as prescribed. Your doctor can provide more information about how your medication works and why it is recommended for you.

When it comes to the treatment of systolic heart failure, there are several potential options that can help manage the condition and improve outcomes. These treatments can be grouped into lifestyle behavior changes, medications, and therapeutic procedures. Let's take a closer look at each category:

• Lifestyle behavior changes:
• Smoking cessation: Quitting smoking is highly recommended for individuals with systolic heart failure. Smoking can worsen heart function and increase the risk of complications.
• Alcohol moderation: Limiting alcohol intake is important as excessive alcohol consumption can weaken the heart muscle.
• Nutrition and diet changes: Following a heart-healthy diet, low in sodium and saturated fats, can help reduce extra sodium and water buildup in the body and lower blood pressure.
• Activity changes: Engaging in regular physical activity, as recommended by a healthcare professional, can improve heart function and overall cardiovascular health.
• Medications:
• Diuretics: These medications help reduce fluid buildup in the body by increasing urine production. They can relieve symptoms such as swelling and shortness of breath.
• ACE inhibitors (Angiotensin-Converting Enzyme inhibitors): ACE inhibitors lower blood pressure and reduce strain on the heart. They also help widen blood vessels, making it easier for the heart to pump blood.
• Beta-blockers: Beta-blockers slow down the heart rate and lower blood pressure. They can improve heart function and reduce symptoms.
• ARNI (Angiotensin Receptor-Neprilysin Inhibitor): ARNI is a combination medication that lowers blood pressure and reduces fluid buildup. It has been shown to reduce the risk of death due to heart failure.
• ARBs (Angiotensin Receptor Blockers): ARBs are a different option for individuals who cannot tolerate ACE inhibitors. They also help lower blood pressure.
• MRAs (Mineralocorticoid Receptor Antagonists): MRAs lower blood pressure and reduce extra sodium and water buildup in the body. They are often used in combination with other medications.
• SGLT2 inhibitors (Sodium-Glucose Co-Transporter 2 inhibitors): Originally used for diabetes treatment, SGLT2 inhibitors have shown benefits in people with heart failure by reducing the risk of death and hospitalization.
• Therapeutic Procedures: In severe cases of systolic heart failure, therapeutic procedures may be necessary. These can include:
  • Cardiac resynchronization therapy (CRT): CRT involves placing a device in the chest that helps different parts of the heart beat in sync, which improves how well the heart pumps blood.
• Implantable cardioverter-defibrillator (ICD): An ICD is a device that monitors the heart's rhythm and delivers an electric shock if a life-threatening irregular heartbeat (arrhythmia) occurs.
• Ventricular assist device (VAD): In severe cases, a device is implanted that helps the heart pump blood to the body.
• Heart transplant: In very advanced cases where other treatments have not been effective, a heart transplant may be considered.

It's important to note that these treatment options should be discussed with a healthcare professional who can provide personalized recommendations based on an individual's specific condition.

Medication dosing may be affected by many factors. Check with your health care professional about dosing for your individual situation. Other side effects can occur. Check with your health care professional or read the information provided with your medication for additional side effect information.