About Nasal and Sinus Cancer

Overview

Nasal and sinus cancer refers to tumors that develop in the paranasal sinuses or nasal cavities. These tumors are relatively rare and may go undetected until they grow large enough to block the airway or spread beyond the nose. The paranasal sinuses are hollow, air-filled spaces in the bones around the nose, while the nasal cavities are the passages behind the nose.

Symptoms of nasal and sinus cancer can include congestion, postnasal drip, pain around the eyes, nosebleeds, decreased sense of smell, mucus running from the nose, and a blocked nose affecting one side of the face. Early symptoms can be similar to those of less serious conditions like a common cold or sinus infection. If left untreated, nasal and sinus cancer can put pressure on the eye, nerves, and other tissues. Diagnosis is typically made through tests that examine the sinuses and nasal cavity. Treatment options depend on various factors and should be discussed with a healthcare professional.

Causes and Risk Factors

The root causes of nasal and sinus cancer are not fully understood, but there are several potential factors that may contribute to its development.

Non-modifiable risk factors cannot be changed or controlled. These include:

  • Age: The risk of developing nasal and sinus cancer tends to increase after age 40.
  • Sex: Men are about twice as likely as women to develop nasal and sinus cancer.
  • Inherited or acquired gene mutations: Certain gene mutations may increase the risk of developing nasal and sinus cancer.

Modifiable risk factors can be influenced or changed. These include:

  • Smoking: Tobacco usage is the biggest modifiable risk factor for developing head and neck cancers, including nasal and sinus cancer.
  • Alcohol: Heavy alcohol use increases risk
  • Exposure to certain chemicals and substances: Being exposed to certain workplace chemicals or dust, such as those found in furniture-making, sawmill work, woodworking, shoemaking, metal-plating, flour mill or bakery work, can increase the risk.
  • Unsafe sex practices: This increases the risk of human papillomavirus (HPV) infection, a sexually-transmitted infection. Some strains of HPV have been associated with an increased risk of nasal and sinus cancer.

It's important to note that these risk factors do not guarantee the development of nasal and sinus cancer. It's always best to consult with a healthcare professional for personalized advice.

Symptoms

Common symptoms of nasal and sinus cancer include:

  • Blocked nose on one side
  • Nosebleeds
  • Decreased sense of smell
  • Constant runny nose
  • Postnasal drip (mucus draining into the back of the nose and throat)

As nasal and sinus cancer progresses or reaches higher severity, additional symptoms may occur, such as:

  • Eye-related symptoms: Complete or partial loss of sight, bulging of one eye, double vision, pain above or below the eye, constant watery eyes, swelling of the conjunctiva (tissue covering the white of the eye)
  • Headaches
  • Loose teeth
  • Pain or pressure affecting one ear
  • Difficulty opening the mouth
  • Lump or growth on the face
  • Persistent facial pain or numbness
  • Swollen lymph nodes in the neck
  • Hearing loss

It's important to note that these symptoms can also be caused by other conditions. If you experience any concerning symptoms, it's best to consult with a healthcare professional for an accurate diagnosis.

Diagnosis

To diagnose nasal and sinus cancer, doctors commonly perform the following examinations, tests, and procedures:

  • Medical history review: The doctor will ask about your personal and family health history.
  • Physical examination: The doctor will examine your nose, face, and neck for any abnormal areas or lumps.
  • Sinus endoscopy: A thin tube with a camera is inserted into your nasal cavity to examine your sinuses in detail.
  • Biopsy: A small piece of tissue is removed for laboratory analysis to determine if it is cancerous.
  • Imaging tests: These tests help visualize the size and location of tumors. They may include X-rays, computed tomography (CT) scans, magnetic resonance imaging (MRI), or positron emission tomography (PET) scans.

To determine the stage or severity of nasal and sinus cancer, additional examinations, tests, and procedures may be performed:

  • Fine-needle aspiration: A thin needle is used to remove fluid from a lymph node to check if cancer has spread.
  • Blood work: Elevated levels of certain proteins and blood cells can indicate cancer.
  • Additional imaging tests: These may include CT scans, MRI scans, or PET scans to assess the extent of tumor growth.

It's important to note that the specific examinations, tests, and procedures performed may vary depending on individual circumstances. It's best to consult with a healthcare professional for personalized advice.

Treatment Options

The goals of treatment for nasal and sinus cancer are to remove or destroy the cancer cells, relieve symptoms, and improve the quality of life. The specific treatments recommended may vary depending on factors such as the stage and location of the cancer, overall health, and type of cancer.

Here are some medication types, therapies, therapeutic procedures, health behavior changes, and other treatments that may be recommended. People may receive more than one treatment for nasal and sinus cancer.

  • Surgery: Removal of the tumor through endoscopic microsurgery or other surgical procedures
  • Radiation therapy: The use of high-energy beams to shrink the tumor before surgery or kill remaining cells after surgery
  • Chemotherapy: Chemical drug therapy used to kill cancer cells. It may be used in combination with radiation therapy for certain types of sinus cancers.
  • Clinical trials: Participation in research studies evaluating new treatments for nasal and sinus cancer.
  • Palliative therapy: Treatment aimed at relieving symptoms and improving quality of life.

Each treatment works differently to achieve the treatment goals. Surgery aims to physically remove the tumor from the nasal and sinus cavities. Radiation therapy uses high-energy beams to destroy cancer cells. Chemotherapy targets cancer cells throughout the body. Clinical trials offer access to innovative treatments that may improve outcomes. Palliative therapy focuses on symptom relief and improving quality of life.

Remember, treatment plans are individualized, so it's important to consult with a healthcare professional for personalized advice.

Medication dosing may be affected by many factors. Check with your health care professional about dosing for your individual situation. Other side effects can occur. Check with your health care professional or read the information provided with your medication for additional side effect information.