BRCA Genes and Cancer

Overview

BRCA genes, specifically BRCA1 and BRCA2, are linked with a higher chance of developing certain types of cancer, particularly breast and ovarian cancer. These genes are considered tumor suppressor genes, which means they help prevent the formation of tumors when they're functioning properly.

• Each person has two copies of the BRCA genes, one from their mother and one from their father. When there is a harmful change or mutation in either of these genes, the risk for cancer significantly increases. If someone inherits a harmful change in a BRCA gene, they have a higher chance of getting several types of cancer, especially breast and ovarian cancer.
• Having a mutation in the BRCA gene can increase the risk of breast cancer by about 45 to 65 percent, while the risk of ovarian, fallopian tube, or peritoneal cancer increases by 39 percent. It's important to note that while a BRCA mutation is rare, it can significantly impact an individual's risk for developing these types of cancers.
• To find out if someone is at an increased risk due to BRCA gene mutations, genetic testing can be done. If someone inherits a harmful change in a BRCA gene, they have a higher chance of getting several types of cancer, especially breast and ovarian cancer.

It's important to consult with a healthcare professional before pursuing any genetic testing or making any medical decisions based on the results. They can provide guidance and support based on an individual's specific situation and family history.