About Rheumatoid Nodules

Overview

Rheumatoid nodules are firm lumps that develop under the skin in about 20% of people with rheumatoid arthritis (RA). They typically appear near joints affected by RA and can range in size from small peas to large walnuts. Rheumatoid nodules are usually painless unless they put pressure on nerves or become inflamed.

Risk factors for developing rheumatoid nodules include severe RA, taking certain arthritis medications like methotrexate, smoking, sustaining an injury near a pressure point, and having specific genes.

While treatment for rheumatoid nodules is not always necessary, there are options available. Disease-modifying antirheumatic drugs (DMARDs) and biological therapies may help reduce the chances of nodules appearing. If nodules develop during RA treatment, anti-inflammatory agents like hydroxychloroquine and prednisolone may be added to reduce their size. In some cases, corticosteroid injections or surgical removal may be recommended if the nodules are painful, infected, or ulcerated.

Remember to consult your doctor for personalized advice as medication dosing may be affected by many factors. Other side effects can occur, so it's important to discuss with your healthcare professional or read the information provided with your medication for additional side effect information.